Basic Information
VIS ID
TVIS44000452
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
104360439/103348211 (Hg38)
End
104360439/103348211 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA8A
Nearest miRNA
hsa-mir-12123/Upstream/193522; hsa-mir-10400/Downstream/1136158;
Nearest TSS
ENST00000518652/Upstream/48257; ENST00000415886/Downstream/23304;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/48819, chr8-CpG: 74/Downstream/22970
Nearby gene
FZD6(+15345) ;
Upstream sequence
ATCACCTTACACCACTTTCAAACAGATAAACTGGTGGAGGACTCTATAAGTGAAGATTTATCACAAGAATTGAGCCTTTCTTTTTTAGTGTACAAACAAA
Downstream sequence
GAACACACCACTGGAAATAAAGACCAGTATGGAAACAAACAACCAGTGAACTGAAGTGCAATAATGATGATGATTATAGAGGTACGGTAGCAATCATGAA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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