Basic Information
VIS ID
TVIS44000456
Fusion event
HTLV-1-ZCCHC7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
37301392/37301395 (Hg38)
End
37301392/37301395 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZCCHC7
miRNAs that regulate target gene
hsa-mir-365a-3p
Nearest miRNA
hsa-mir-101-2/Upstream/407864; hsa-let-7a-1/Downstream/3627615;
Nearest TSS
ENST00000422679/Upstream/17232; ENST00000497924/Downstream/24639;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/180407, chr9-CpG: 44/Downstream/121176
Upstream sequence
GGTTATAGAAGTAAGGGGTTATGCCTCTTgctgtggcacaccacagatgccagcactttgggaggctgaagtgggtggatctcttgagctcaggagtttg
Downstream sequence
agaccagcctgggtgacatggtgaaaccctgtctctaccaaaaaaattataaaaattagcctagcgtggtggcaagttcctgtagtcccagctactcagg
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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