Basic Information
VIS ID
TVIS44000471
Fusion event
HTLV-1-LOC105378339 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
67601160/65841402 (Hg38)
End
67601160/65841402 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
LOC105378339
Nearest miRNA
hsa-mir-1265/Upstream/2468354; hsa-mir-107/Downstream/1561949;
Nearest TSS
ENST00000439456/Upstream/225665; ENST00000608793/Downstream/237701;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/787099, chr10-CpG: 39/Downstream/1922683
Nearby gene
CTNNA3(-71116) ;
Upstream sequence
ctggggtgacagagtgacactccatctcaaaacaaaacaaaaaaacactaacatatctccaaatacaaatagacaaatccactatcgttaattgatagtc
Downstream sequence
tgattaattgataactcaagcgggcagaaatccattaagtatatacatgatctgaccagcactaacaatcaattcaatctaattgtcatttatataatac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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