Basic Information
VIS ID
TVIS44000484
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.32
Reference genome
GRCh37/hg19
Start
4265156/4155990 (Hg38)
End
4265156/4155990 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3649/Upstream/2495610; hsa-let-7i/Downstream/2807709;
Nearest TSS
ENST00000382841/Upstream/130005; ENST00000541542/Downstream/117782;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/124652, chr12-CpG: 54/Downstream/8663
Nearby gene
CCND2-AS1(No orient, 92777)
Upstream sequence
gggattacaggcgtgagccaccacacccggcctgacttttttttgagtacagtcttccctccttttttgtgagttgttccttgtttgggttttccgatgc
Downstream sequence
cttttcacgatcaggtcaggGTGTTCTGAGTGTCTGGGTAGAGTTAGGTTCCTTCAGTGGCCGCAGTCTGGCCTTTCTCTGGTGGAAATGAGTGCGGTTT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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