Basic Information
VIS ID
TVIS44000501
Fusion event
HTLV-1-RNF40 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
End
30810235/30798914 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-let-7b-5p ; hsa-mir-1229-3p ; hsa-mir-769-5p ; hsa-mir-331-3p ; hsa-mir-186-5p ; hsa-mir-92a-3p ; hsa-mir-4707-3p ; hsa-mir-6761-3p ; hsa-mir-1226-3p ; hsa-mir-1227-5p ; hsa-mir-1249-5p ; hsa-mir-1252-5p ; hsa-mir-1262 ; hsa-mir-1264 ; hsa-mir-1270 ; hsa-mir-128-1-5p ; hsa-mir-128-2-5p ; hsa-mir-185-3p ; hsa-mir-296-5p ; hsa-mir-3151-5p ; hsa-mir-3179 ; hsa-mir-3202 ; hsa-mir-3919 ; hsa-mir-4278 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-450a-1-3p ; hsa-mir-4525 ; hsa-mir-4641 ; hsa-mir-4683 ; hsa-mir-4694-3p ; hsa-mir-4701-3p ; hsa-mir-4716-3p ; hsa-mir-4747-5p ; hsa-mir-4802-5p ; hsa-mir-5001-5p ; hsa-mir-5010-5p ; hsa-mir-5186 ; hsa-mir-5196-5p ; hsa-mir-539-5p ; hsa-mir-541-3p ; hsa-mir-5680 ; hsa-mir-5787 ; hsa-mir-6085 ; hsa-mir-615-5p ; hsa-mir-620 ; hsa-mir-651-3p ; hsa-mir-6515-5p ; hsa-mir-654-5p ; hsa-mir-655-5p ; hsa-mir-6724-5p ; hsa-mir-6732-5p ; hsa-mir-6736-5p ; hsa-mir-6748-5p ; hsa-mir-6752-3p ; hsa-mir-6756-5p ; hsa-mir-6762-5p ; hsa-mir-6766-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6773-5p ; hsa-mir-6789-5p ; hsa-mir-6794-5p ; hsa-mir-6797-5p ; hsa-mir-6804-5p ; hsa-mir-6805-5p ; hsa-mir-6813-5p ; hsa-mir-6824-5p ; hsa-mir-6845-5p ; hsa-mir-6890-5p ; hsa-mir-7150 ; hsa-mir-762 ; hsa-mir-7704 ; hsa-mir-92a-2-5p ; hsa-mir-224-3p ; hsa-mir-27a-5p ; hsa-mir-2861 ; hsa-mir-3920 ; hsa-mir-4447 ; hsa-mir-4472 ; hsa-mir-4738-3p ; hsa-mir-522-3p ; hsa-mir-6076 ; hsa-mir-6134 ; hsa-mir-6751-5p ; hsa-mir-6752-5p ; hsa-mir-6797-3p ; hsa-mir-6803-5p ; hsa-mir-6835-5p ; hsa-mir-6842-5p ; hsa-mir-6881-5p ; hsa-mir-7110-5p ; hsa-mir-7854-3p
Nearest miRNA
hsa-mir-1225/Upstream/294913; hsa-mir-11401/Downstream/76352;
Nearby gene
ZNF629(-11712) ;
Upstream sequence
tagtagagacagggtttcaccatgttggccaggctggtcttgaacttctcgacctctggtgatccacttgcctcggcctcccaaagtgctggcattatag
Downstream sequence
gcatgagtcaccgcacccggccTAACCAGTGCTTAAAATTTGACATTCTCTAGATTAAGGCTGGGACATATGATTTGTAATAGTGGCtttatttatttat
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate