Basic Information
VIS ID
TVIS44000508
Fusion event
HTLV-1-NFE2L1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
End
46136173/48058811 (Hg38)
Orient
-
Location type
Exonic
Target gene
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-342-5p ; hsa-mir-18a-3p ; hsa-mir-484 ; hsa-mir-324-3p ; hsa-mir-185-5p ; hsa-mir-30c-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-1260b ; hsa-mir-6873-3p ; hsa-mir-6867-3p ; hsa-mir-6826-3p ; hsa-mir-421 ; hsa-mir-7158-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6845-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-6795-3p ; hsa-mir-6887-3p ; hsa-mir-4709-5p ; hsa-mir-3912-5p ; hsa-mir-8057 ; hsa-mir-106a-3p ; hsa-mir-198 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4634 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6812-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-652-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-6892-3p ; hsa-mir-3607-5p ; hsa-mir-1207-5p ; hsa-mir-1226-5p ; hsa-mir-1249-5p ; hsa-mir-1273f ; hsa-mir-1909-3p ; hsa-mir-2682-5p ; hsa-mir-31-5p ; hsa-mir-34a-5p ; hsa-mir-34b-5p ; hsa-mir-34c-5p ; hsa-mir-3616-3p ; hsa-mir-3688-5p ; hsa-mir-3714 ; hsa-mir-4419a ; hsa-mir-4436b-3p ; hsa-mir-4470 ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-449c-5p ; hsa-mir-4510 ; hsa-mir-4519 ; hsa-mir-4534 ; hsa-mir-4632-5p ; hsa-mir-4708-3p ; hsa-mir-4710 ; hsa-mir-4721 ; hsa-mir-4763-3p ; hsa-mir-5693 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6514-5p ; hsa-mir-6721-5p ; hsa-mir-6722-3p ; hsa-mir-6735-5p ; hsa-mir-6760-5p ; hsa-mir-6782-5p ; hsa-mir-6797-5p ; hsa-mir-6809-5p ; hsa-mir-6838-5p ; hsa-mir-6879-5p ; hsa-mir-7112-5p ; hsa-mir-7843-5p ; hsa-mir-8082 ; hsa-mir-3617-5p ; hsa-mir-4540 ; hsa-mir-548c-3p ; hsa-mir-548u ; hsa-mir-641 ; hsa-mir-6838-3p ; hsa-mir-7161-5p
Nearest miRNA
hsa-mir-10226/Upstream/21564; hsa-mir-10a/Downstream/97616;
Nearest CpG islands
Upstream sequence
GTGCAGGCCTCCCAGCTGGAGGAGGAATTTGACTCTGACTCAGGCCTTTCCTTAGACTCGAGCCATAGCCCTTCTTCCCTAAGCAGCTCTGAAGGCAGtt
Downstream sequence
cttcctcttcttcctcctcctcttcctcttcttcctctgcttcttcctctgcctcttcctccttttctGAGGAAGGTGCGGTTGGCTACAGCTCTGACTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate