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TVIS44000508
Basic Information
VIS ID
TVIS44000508
Fusion event
HTLV-1-NFE2L1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
46136173/48058811 (Hg38)
End
46136173/48058811 (Hg38)
Orient
-
Location type
Exonic
Target gene
NFE2L1
miRNAs that regulate target gene
hsa-mir-218-5p
;
hsa-mir-342-5p
;
hsa-mir-18a-3p
;
hsa-mir-484
;
hsa-mir-324-3p
;
hsa-mir-185-5p
;
hsa-mir-30c-5p
;
hsa-mir-99a-5p
;
hsa-mir-92a-3p
;
hsa-mir-1260b
;
hsa-mir-6873-3p
;
hsa-mir-6867-3p
;
hsa-mir-6826-3p
;
hsa-mir-421
;
hsa-mir-7158-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6845-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
;
hsa-mir-6795-3p
;
hsa-mir-6887-3p
;
hsa-mir-4709-5p
;
hsa-mir-3912-5p
;
hsa-mir-8057
;
hsa-mir-106a-3p
;
hsa-mir-198
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-4634
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6812-3p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-652-3p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-6791-5p
;
hsa-mir-4292
;
hsa-mir-4308
;
hsa-mir-6892-3p
;
hsa-mir-3607-5p
;
hsa-mir-1207-5p
;
hsa-mir-1226-5p
;
hsa-mir-1249-5p
;
hsa-mir-1273f
;
hsa-mir-1909-3p
;
hsa-mir-2682-5p
;
hsa-mir-31-5p
;
hsa-mir-34a-5p
;
hsa-mir-34b-5p
;
hsa-mir-34c-5p
;
hsa-mir-3616-3p
;
hsa-mir-3688-5p
;
hsa-mir-3714
;
hsa-mir-4419a
;
hsa-mir-4436b-3p
;
hsa-mir-4470
;
hsa-mir-449a
;
hsa-mir-449b-5p
;
hsa-mir-449c-5p
;
hsa-mir-4510
;
hsa-mir-4519
;
hsa-mir-4534
;
hsa-mir-4632-5p
;
hsa-mir-4708-3p
;
hsa-mir-4710
;
hsa-mir-4721
;
hsa-mir-4763-3p
;
hsa-mir-5693
;
hsa-mir-6127
;
hsa-mir-6129
;
hsa-mir-6130
;
hsa-mir-6133
;
hsa-mir-6514-5p
;
hsa-mir-6721-5p
;
hsa-mir-6722-3p
;
hsa-mir-6735-5p
;
hsa-mir-6760-5p
;
hsa-mir-6782-5p
;
hsa-mir-6797-5p
;
hsa-mir-6809-5p
;
hsa-mir-6838-5p
;
hsa-mir-6879-5p
;
hsa-mir-7112-5p
;
hsa-mir-7843-5p
;
hsa-mir-8082
;
hsa-mir-3617-5p
;
hsa-mir-4540
;
hsa-mir-548c-3p
;
hsa-mir-548u
;
hsa-mir-641
;
hsa-mir-6838-3p
;
hsa-mir-7161-5p
Nearest miRNA
hsa-mir-10226/Upstream/21564; hsa-mir-10a/Downstream/97616;
Nearest TSS
ENST00000595228/Upstream/2859;
ENST00000581319/Downstream/66;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/9940
,
chr17-CpG: 28/Downstream/476
Upstream sequence
GTGCAGGCCTCCCAGCTGGAGGAGGAATTTGACTCTGACTCAGGCCTTTCCTTAGACTCGAGCCATAGCCCTTCTTCCCTAAGCAGCTCTGAAGGCAGtt
Downstream sequence
cttcctcttcttcctcctcctcttcctcttcttcctctgcttcttcctctgcctcttcctccttttctGAGGAAGGTGCGGTTGGCTACAGCTCTGACTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL7-CR1
Sample type
Nontumor
Age
59
Gender
Female
CpG Island Information
×
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