Basic Information
VIS ID
TVIS44000523
Fusion event
HTLV-1-PTPRA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p13
Reference genome
GRCh37/hg19
Start
2886094/2905448 (Hg38)
End
2886094/2905448 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTPRA
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-1292/Upstream/252606; hsa-mir-1-1/Downstream/1012046;
Nearest TSS
ENST00000382410/Upstream/31765; ENST00000356147/Downstream/17759;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/31459, chr20-CpG: 98/Downstream/140183
Upstream sequence
aatgtttcctaagaaaagttgaacactcatggctggttggctgctctctagcacatcttgccttcgtctctcactagttgaattttacacttccaggggt
Downstream sequence
cagtatgtttgttccaaatctgcttatgccagttacatttagtactgtaattttataatttaattaaacattaactaatgaaatatgactgcaaaaagta
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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