Basic Information
VIS ID
TVIS44000526
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
9831755/9851107 (Hg38)
End
9831755/9851107 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/2479415; hsa-mir-1-1/Downstream/798529;
Nearest TSS
ENST00000382410/Upstream/12066; ENST00000449270/Downstream/134981;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/11894, chr20-CpG: 35/Downstream/183855
Nearby gene
PAK5(-12068) ;
Nearest cancer related gene
PAK5(OG, -12068) ;
Upstream sequence
agaatacactgctctttcttcaagatcctggttgtgatagtgtactatagttttgcaagatgttggggaaagctagattaagaatacactgctctttctg
Downstream sequence
catttcttacaactacatgggaatctacaattatctcaaaaagaatttcaattACAAAGTAATTCATggccaggtgcagtggctcacgcctgtaatccca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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