Basic Information
VIS ID
TVIS44000552
Fusion event
HTLV-1-FAM174A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
99877635/100541931 (Hg38)
End
99877635/100541931 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5F
Target gene
FAM174A
Nearest miRNA
hsa-mir-10397/Upstream/4462719; hsa-mir-103a-1/Downstream/274551;
Nearest TSS
ENST00000502646/Upstream/6549; ENST00000505792/Downstream/20121;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/5915, chr5-CpG: 32/Downstream/358932
Upstream sequence
ATTTTCCCCTTTTCTGTAGCACTCAGTGCACTGGTTCTTACTTTGACTTCTGAGACATCTCTTCTGATTTtcttcttacctccttgagtatttcttgcct
Downstream sequence
agcttcttcatgaatttcttattccatgaactcttcttcctaattaggactcttctacaagctaatgtctggagagcagggcctctgtcttactcatctt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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