Basic Information
VIS ID
TVIS44000573
Fusion event
HTLV-1-DPYS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
105466472/104454244 (Hg38)
End
105466472/104454244 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8A
Target gene
DPYS
Nearest miRNA
hsa-mir-12123/Upstream/1299555; hsa-mir-10400/Downstream/30125;
Nearest TSS
ENST00000518652/Upstream/9876; ENST00000521923/Downstream/12800;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/86486, chr8-CpG: 78/Downstream/12200
Upstream sequence
ggaacctgaagcaggtggatcacctgaggtcaggagttcaagacaagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaattagctgg
Downstream sequence
gcatggtggcgggtgcctataatcccagctactagggaggctgaggcaggagaattgcttgaacccatgaggcagaggttgcggtgagccgagatcatgc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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