Basic Information
VIS ID
TVIS44000579
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
83605407/80990492 (Hg38)
End
83605407/80990492 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/10180408; hsa-let-7a-1/Downstream/2979256;
Nearest TSS
ENST00000422679/Upstream/119197; ENST00000413050/Downstream/623030;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1416847, chr9-CpG: 255/Downstream/696732
Nearby gene
TLE1(-593191) ;
Nearest cancer related gene
TLE1(OG, -593191) ;
Upstream sequence
gaggctgaggcagacggattacttgaggtcaggagttcgagaccagcctggtcaatatggtgaaactctgtctctaccaaaaaatacaaaaattagctgg
Downstream sequence
atgtggtggtgtgtgcctgtaatcccagctactaaggaggctgaggcaggaaaatcgcttgaacccaggaggcagaagttgcagtgagctgagattgcac
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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