Basic Information
VIS ID
TVIS44000587
Fusion event
HTLV-1-RGL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
183767750/183798616 (Hg38)
End
183767750/183798616 (Hg38)
Orient
+
Location type
Intronic
Target gene
RGL1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/3360226; hsa-mir-1182/Downstream/8917712;
Nearest TSS
ENST00000473358/Upstream/43679; ENST00000360851/Downstream/6504;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/162418, chr1-CpG: 140/Downstream/237609
Upstream sequence
tagtatattcttattattttgtgtgtgtatgtgaagatcacttaacataagatctaccctctcagaaaattttaagtatataatagagtattggtagcta
Downstream sequence
ttaggcactgtgttatagacctgtagtagatccctagaaggtattcatcttgtataattgaaacttggcaccctttgaccatcaccaccacatttctccc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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