Basic Information
VIS ID
TVIS44000589
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh37/hg19
Start
25327247/25000756 (Hg38)
End
25327247/25000756 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/81340; hsa-mir-101-1/Downstream/22747;
Nearest TSS
ENST00000473358/Upstream/29891; ENST00000455902/Downstream/112363;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/68242, chr1-CpG: 45/Downstream/231316
Nearby gene
MIR4425(+22747) ;
Upstream sequence
TGACTAGAAATGCACTTTGGCTCTCGAGGGCAGAGGGGACAGCCTGTCATTGTCctctaccacttccttgctgtgtaatgttgagcaagtttcttaattt
Downstream sequence
ctctgggcctcagtttccatgtaaatggcagtataaccatacctccttcccagggctttcggggaggatctggtgaaaagatgcTGCAGGGAGACTACGT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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