Basic Information
VIS ID
TVIS44000611
Fusion event
HTLV-1-C12orf50 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
88415994/88022217 (Hg38)
End
88415994/88022217 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
C12orf50
Nearest miRNA
hsa-let-7i/Upstream/1277068; hsa-mir-1178/Downstream/6539572;
Nearest TSS
ENST00000382841/Upstream/205731; ENST00000552803/Downstream/5746;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2741295, chr12-CpG: 52/Downstream/13111
Upstream sequence
cagcagcacatcaaaaagctaatccatcatgatcaagtatgccatatccttgggatgcaaggtgggttcaacatatacaaatcaataaatgtgactgact
Downstream sequence
acataaacagaactaaaagtaaaaaccatattgagatatgattacctcaatagatgcagaaaaggcttttaataaaattcaacatcccttcatgctaaaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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