Basic Information
VIS ID
TVIS44000629
Fusion event
HTLV-1-SNHG14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
25553117/25307970 (Hg38)
End
25553117/25307970 (Hg38)
Orient
+
Location type
Intronic
Target gene
SNHG14
Nearest miRNA
hsa-mir-1268a/Upstream/1745839; hsa-mir-10393/Downstream/540777;
Nearest TSS
ENST00000557528/Upstream/220309; ENST00000557558/Downstream/38061;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/352063, chr15-CpG: 143/Downstream/130278
Nearby gene
UBE3A(-29279) ;
Upstream sequence
tcttctaatttcttccttgacctattggttatttaaatgtatttaatttttgcatattgtggatttcccagttttccttctgttattgatttctagtttt
Downstream sequence
attccattgtgatcacagaagatattttgtataatcgcagtctattaacatttattaagtcttgtggcctaacagaggatctatgttggagaatgttcca
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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