Basic Information
VIS ID
TVIS44000642
Fusion event
HTLV-1-PIEZO2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
11072582/11072583 (Hg38)
End
11072582/11072583 (Hg38)
Orient
+
Location type
Intronic
Target gene
PIEZO2
Nearest miRNA
hsa-mir-3976/Upstream/312934; hsa-mir-1-2/Downstream/582302;
Nearest TSS
ENST00000575820/Upstream/178966; ENST00000591029/Downstream/76005;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/345914, chr18-CpG: 169/Downstream/75725
Upstream sequence
AAAGTCGCTCACATGATTGTACCATCTTAAAGAGCATGCATAGTGCATGTAACTATTCATTTATGTTagtaatagctcatactaatgtgcttactgtgtg
Downstream sequence
acaagcccggatctatgcatttcacgtcaattaactcttgtagttattatcatcattttacaaagtcttttatttctttttacatgtgaagaagcaggcc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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