Basic Information
VIS ID
TVIS44000651
Fusion event
HTLV-1-ERMN integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
158181901/157325389 (Hg38)
End
158181901/157325389 (Hg38)
Orient
+
Location type
Intronic
Target gene
ERMN
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-128-1/Upstream/5956978; hsa-mir-10b/Downstream/1861446;
Nearest TSS
ENST00000437798/Upstream/23903; ENST00000604340/Downstream/270;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/888892, chr2-CpG: 31/Downstream/271898
Upstream sequence
AAGGGCTACATTTTTGGGGTGTCCAGCTCATTTCGATAATAGTTTATCAAAAAAATCCAGGGTAAATTTATAAGTCAAAACAAGAAAATTAAGGAGAAGG
Downstream sequence
GAAACACTTTACCTTTTAGCATTTTGTCCTCCATGGATGAGTTGAGCAGCATGTTCCCTTGTAATTTTCTTCTTTCCTCCTGACTTCCTTTGGTGAGTGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate