Basic Information
VIS ID
TVIS44000655
Fusion event
HTLV-1-FTCDNL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
200611787/199747064 (Hg38)
End
200611787/199747064 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2I
Target gene
FTCDNL1
Nearest miRNA
hsa-mir-10b/Upstream/10613953; hsa-mir-1244-1/Downstream/7036170;
Nearest TSS
ENST00000437798/Upstream/115333; ENST00000319974/Downstream/101906;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/87583, chr2-CpG: 85/Downstream/103601
Nearby gene
FTCDNL1(No orient, 13472)
Upstream sequence
attttgttcagccagcattgacatgaacaatatcctgtttcagagaagagggtttatttaaaacacacacacacacacacacacacacacacacacacac
Downstream sequence
atacacacacaaaacaaaatccctcataaagatccttgaacatcagatgactcttacaaaacaatttgatgaattaagtgtaaatgaatcaggaacatgt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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