Basic Information
VIS ID
TVIS44000656
Fusion event
HTLV-1-CAMKMT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
GRCh37/hg19
Start
44941380/44714241 (Hg38)
End
44941380/44714241 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
CAMKMT
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1301/Upstream/9242755; hsa-mir-10b/Downstream/2663434;
Nearest TSS
ENST00000437798/Upstream/9956; ENST00000260653/Downstream/208798;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/352022, chr2-CpG: 19/Downstream/54284
Upstream sequence
agagaaaacatacgcaacagggtcttttgtggttgttagagttaggccacacatttggctctgagttgcacaggtgctggagcaaagaaaaagaggatca
Downstream sequence
actctaagagttatagtgccaggaagtggaagcaacatcccttgatctgcagaccagcctttcctggtgctgaaacctgactattttttccaacaggccc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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