Basic Information
VIS ID
TVIS44000659
Fusion event
HTLV-1-LOC730100 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
52266700/52039562 (Hg38)
End
52266700/52039562 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC730100
Nearest miRNA
hsa-mir-1301/Upstream/1343300; hsa-mir-10b/Downstream/662960;
Nearest TSS
ENST00000437798/Upstream/813987; ENST00000435357/Downstream/333556;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1011202, chr2-CpG: 118/Downstream/531703
Nearby gene
MIR4431(-662960) ;
Upstream sequence
gttacatatgtatacatgtgacatgctggtgcgtggcacctactaactcatcatctagcattaggtatatctcccaatgctatccctcccccatcccccc
Downstream sequence
accccacaacagtccccagagtgtgatgttccccttcctgtgtccatgtgttctcattgttcaattcccacctatgagtgagaatatgcagtgtttggtt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate