Basic Information
VIS ID
TVIS44000664
Fusion event
HTLV-1-ITGB2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
46347113/44927198 (Hg38)
End
46347113/44927198 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
ITGB2-AS1
Nearest miRNA
hsa-let-7c/Upstream/1317209; hsa-mir-6815/Downstream/551068;
Nearest TSS
ENST00000624081/Upstream/5872; ENST00000609953/Downstream/1520;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/23161, chr21-CpG: 134/Downstream/4215
Upstream sequence
CCCAGCTTCCACCCCCATAACACACAACCCCAGAGCTTGGGAAGGAGGTCTCTCTGTGACAGGTGGGATTCTGGAAGTTTCCACGGAGGAGACCCCATAG
Downstream sequence
GAGCAGGGTTTGAAGGTCAAGAAAGATGCTAAGGATGGAGAGGGCCAGTGGGGAGAGGGTGGTTCCAGGCTCACTTCACAGAGGTGCTTGGGGAGCTGCA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate