Basic Information
VIS ID
TVIS44000682
Fusion event
HTLV-1-TMPRSS11E integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
69323505/68457787 (Hg38)
End
69323505/68457787 (Hg38)
Orient
+
Location type
Intronic
Target gene
TMPRSS11E
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-12113/Upstream/2180859; hsa-mir-1243/Downstream/8115781;
Nearest TSS
ENST00000502981/Upstream/10338; ENST00000510647/Downstream/4034;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/107584, chr4-CpG: 55/Downstream/2230350
Upstream sequence
ttcttcaatgatagactggataaagaaaacatggcacatatacaccatggaatactatgcagccataaaagaggatgagttcatgttctttgcagggaca
Downstream sequence
cggatgaagccggaaaccatcattctcagcaaactaacacaggaacagaaaaccaaatactgcatgttttcactcataagtgggagttaaacaatgagaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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