VISDB Viral Integration Site DataBase

VIS ID

TVIS44000704

Fusion event

HTLV-1-FOXK1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr7

Cytoband

p22.1

Reference genome

Start

End

4717410/4677779 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-186-5p ; hsa-let-7b-5p ; hsa-mir-1229-3p ; hsa-mir-615-3p ; hsa-mir-149-5p ; hsa-mir-15b-5p ; hsa-mir-203a-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-630 ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548k ; hsa-mir-548l ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-3607-5p ; hsa-mir-3908 ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-4495 ; hsa-mir-4524a-5p ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-4524b-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-5589-3p ; hsa-mir-548av-5p ; hsa-mir-548ay-5p ; hsa-mir-6838-5p ; hsa-mir-8054 ; hsa-mir-548bb-5p ; hsa-mir-6758-3p ; hsa-mir-137 ; hsa-mir-503-5p ; hsa-mir-561-5p ; hsa-mir-5692c ; hsa-mir-5681b ; hsa-mir-5692a ; hsa-mir-5701 ; hsa-mir-5692b ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-944 ; hsa-mir-646 ; hsa-mir-218-5p ; hsa-mir-570-3p ; hsa-mir-4501 ; hsa-mir-1537-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-4253 ; hsa-mir-6862-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-6740-3p ; hsa-mir-1251-3p ; hsa-mir-103b ; hsa-mir-6830-5p ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-362-3p ; hsa-mir-4713-5p ; hsa-mir-663b ; hsa-mir-7155-3p ; hsa-mir-3136-3p ; hsa-mir-6499-3p ; hsa-mir-17-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-5693 ; hsa-mir-4257 ; hsa-mir-3677-5p ; hsa-mir-4749-3p ; hsa-mir-7108-3p ; hsa-mir-6887-3p ; hsa-mir-4640-3p ; hsa-mir-3692-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p ; hsa-mir-1199-3p ; hsa-mir-1252-5p ; hsa-mir-1324 ; hsa-mir-134-3p ; hsa-mir-140-3p ; hsa-mir-1908-3p ; hsa-mir-1914-3p ; hsa-mir-198 ; hsa-mir-2117 ; hsa-mir-22-3p ; hsa-mir-26b-3p ; hsa-mir-3160-3p ; hsa-mir-3177-3p ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3184-5p ; hsa-mir-3196 ; hsa-mir-340-3p ; hsa-mir-3609 ; hsa-mir-3648 ; hsa-mir-3650 ; hsa-mir-3657 ; hsa-mir-3665 ; hsa-mir-3688-3p ; hsa-mir-3689d ; hsa-mir-3714 ; hsa-mir-3934-5p ; hsa-mir-3978 ; hsa-mir-423-5p ; hsa-mir-425-3p ; hsa-mir-4269 ; hsa-mir-4273 ; hsa-mir-4279 ; hsa-mir-4285 ; hsa-mir-432-3p ; hsa-mir-4419a ; hsa-mir-4446-3p ; hsa-mir-4455 ; hsa-mir-4466 ; hsa-mir-4485-5p ; hsa-mir-4487 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4504 ; hsa-mir-4505 ; hsa-mir-4510 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4533 ; hsa-mir-4632-3p ; hsa-mir-4669 ; hsa-mir-4675 ; hsa-mir-4681 ; hsa-mir-4687-3p ; hsa-mir-4694-3p ; hsa-mir-4736 ; hsa-mir-4741 ; hsa-mir-4747-5p ; hsa-mir-4764-5p ; hsa-mir-497-3p ; hsa-mir-5001-5p ; hsa-mir-5194 ; hsa-mir-5196-5p ; hsa-mir-542-3p ; hsa-mir-548ah-5p ; hsa-mir-558 ; hsa-mir-5681a ; hsa-mir-5787 ; hsa-mir-605-3p ; hsa-mir-6078 ; hsa-mir-609 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6134 ; hsa-mir-651-3p ; hsa-mir-6715b-5p ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6741-5p ; hsa-mir-675-5p ; hsa-mir-6760-5p ; hsa-mir-6770-5p ; hsa-mir-6772-5p ; hsa-mir-6776-5p ; hsa-mir-6790-3p ; hsa-mir-6808-5p ; hsa-mir-6816-5p ; hsa-mir-6820-5p ; hsa-mir-6827-3p ; hsa-mir-6851-5p ; hsa-mir-6893-5p ; hsa-mir-7114-5p ; hsa-mir-7156-5p ; hsa-mir-762 ; hsa-mir-764 ; hsa-mir-940 ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-25-5p ; hsa-mir-30b-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-4459 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4728-5p ; hsa-mir-490-3p ; hsa-mir-5186 ; hsa-mir-6087 ; hsa-mir-6516-5p ; hsa-mir-658 ; hsa-mir-6724-5p ; hsa-mir-6773-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7851-3p

Nearest miRNA

hsa-mir-339/Upstream/2150634; hsa-mir-10399/Downstream/110786;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/35293, chr7-CpG: 157/Downstream/4227

Nearby gene

FOXK1(+4520) ;

Upstream sequence

caaagtgctgggattacaggcatgcgccaccgcgcccggccgtcggaaccattttcaagtgcacagatcagtggcatgaagcacattcccagtgctgtgc

Downstream sequence

aatcaacaccatcagccacctccacaatgttctcatcttgcccaacagaaactctgtccttattccacagtaactcccggtctcccctctcccagtcctc