Basic Information
VIS ID
TVIS44000725
Fusion event
HTLV-1-BATF integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
76002762/75536419 (Hg38)
End
76002762/75536419 (Hg38)
Orient
-
Location type
Intronic
Target gene
BATF
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-208a/Upstream/1056215; hsa-mir-1185-1/Downstream/1729799;
Nearest TSS
ENST00000550708/Upstream/13859; ENST00000555058/Downstream/42198;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/107773, chr14-CpG: 28/Downstream/10068
Upstream sequence
cctagagagccttgaggccaagctgcgaggccaggcaaaggtcagaaaggtgcttggtaaggtggagACCAAGTTCAAGACCATAAGGGAGTGAGGAGGA
Downstream sequence
ACTCAGTAATAATGGCAATTGTAGggctgagcacagtggctcacacctgtaatcccagcactttgggaggccgagttggttggatcatttgaggccagga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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