Basic Information
VIS ID
TVIS44000741
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
10749137/10768489 (Hg38)
End
10749137/10768489 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA20B
Nearest miRNA
hsa-mir-103a-2/Upstream/118794; hsa-mir-1-1/Downstream/7702126;
Nearest TSS
ENST00000382410/Upstream/3203; ENST00000603462/Downstream/133795;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/93526, chr20-CpG: 37/Downstream/918385
Upstream sequence
CCTGGGAGCCAGGTCATGGATTAAATTATTAAGTTGAAACTGTCAGAGTGAAGGAGCAAGTTATGAGATTAGTTAAGTAGCATATCAAAGCCAGAGTGGT
Downstream sequence
AACAATGAAAGTAATCCTCCATTCATATAAGAGCCCAATGTCTCTGTAGCTTCATTTTCCTACCTCTTGCCTTCTTCCCACCAACAAAGAGTTGAGATAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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