Basic Information
VIS ID
TVIS44000750
Fusion event
HTLV-1-LOC107985885 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
55852302/55625167 (Hg38)
End
55852302/55625167 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC107985885
Nearest miRNA
hsa-mir-1301/Upstream/1775962; hsa-mir-10b/Downstream/357800;
Nearest TSS
ENST00000437798/Upstream/6287; ENST00000606639/Downstream/22215;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/7237, chr2-CpG: 32/Downstream/68478
Nearby gene
PPP4R3B(No orient, 7442)
Upstream sequence
tgtctcaacatcatgtatagaaaaaacAAATTGAAAATGCTATCTTATCATATTATTTACTAAATTTACATGCATATACATATACATACATAACATATAT
Downstream sequence
CTGAGTTTGAGTCTGAATTCACTACTGTTTCAATTGCTGTAGTTGGTCAATTCTAGTATGACAGAGTTTTAATTGCTACAGTTTTGGAATGATTATGGGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate