Basic Information
VIS ID
TVIS44000780
Fusion event
HTLV-1-SCLT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q28.2
Reference genome
GRCh37/hg19
Start
129821262/128900107 (Hg38)
End
129821262/128900107 (Hg38)
Orient
+
Location type
Intronic
Target gene
SCLT1
Nearest miRNA
hsa-mir-12113/Upstream/3392800; hsa-mir-1305/Downstream/14443353;
Nearest TSS
ENST00000502981/Upstream/68674; ENST00000502360/Downstream/36597;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/87277, chr4-CpG: 56/Downstream/193087
Upstream sequence
gctcaaggaaataaaagaggatacaaacaaatggaagaacattccacacgcatgggtaggaagaatcgataccatgaaaatggccatactgcccaaggta
Downstream sequence
atttatagattcaatgccatccccatcaagctaccaatgactttcttcacagaattggaaaaaactacttgaaagttcatatggaaccaaaaaaagagcc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate