Basic Information
VIS ID
TVIS44000791
Fusion event
HTLV-1-DPH6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q14
Reference genome
GRCh37/hg19
Start
35837199/35544998 (Hg38)
End
35837199/35544998 (Hg38)
Orient
-
Location type
Intronic
Target gene
DPH6
Nearest miRNA
hsa-mir-1233-1/Upstream/172634; hsa-mir-10393/Downstream/381858;
Nearest TSS
ENST00000557528/Upstream/2507; ENST00000560866/Downstream/1155;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/422759, chr15-CpG: 56/Downstream/927
Upstream sequence
GGTACTTTTAATTCTTAAAATAAGACACAATGGTTAAAGCTTAATCATTTATGTTACAGAGGACATTTACTGAACAACAATAATTATTGTGACATTATGG
Downstream sequence
TCTAGTCTCCTAAAAATGACATTGAAGGAAAGGGAACCGGAATATTCCAGACACTACAGTAGGTCTGAAATCTCATATCAAGTCCTTAATAGGTCAAAAC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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