Basic Information
VIS ID
TVIS44000805
Fusion event
HTLV-1-LOC645481 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
26115477/26113855 (Hg38)
End
26115477/26113855 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
LOC645481
Nearest miRNA
hsa-mir-12113/Upstream/1593565; hsa-mir-1243/Downstream/2705727;
Nearest TSS
ENST00000502981/Upstream/43101; ENST00000514656/Downstream/49600;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/84785, chr4-CpG: 20/Downstream/205292
Nearby gene
SMIM20(No orient, 183976)
Upstream sequence
TGTGGGAAAACCTTCTGTGAAAAATCAGCTCTCACCAAACATCAGAGAATTCACACAAGGCCAAAAGGTCTTTCCACATCCTGAATGTTAGAAGCCTTCA
Downstream sequence
TACACCTGTCAAATTTTTGTTCAACTTTTAAAAATTAGAGAAAGCAAAGAATGTCAGAAATTACTAGAAAATGACTTCTTGTTTGAATATGTGAAAGCAT
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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