VISDB Viral Integration Site DataBase

VIS ID

TVIS44000816

Fusion event

HTLV-1-HIVEP3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p34.2

Reference genome

Start

End

42343974/41878303 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-10a-5p ; hsa-mir-26b-5p ; hsa-mir-218-5p ; hsa-mir-149-3p ; hsa-mir-6795-5p ; hsa-mir-6887-5p ; hsa-mir-625-5p ; hsa-mir-486-3p ; hsa-mir-6721-5p ; hsa-mir-92b-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-4524a-3p ; hsa-mir-211-3p ; hsa-mir-6743-5p ; hsa-mir-4688 ; hsa-mir-4524b-3p ; hsa-mir-6079 ; hsa-mir-3118 ; hsa-mir-134-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6081 ; hsa-mir-3192-5p ; hsa-mir-4538 ; hsa-mir-4453 ; hsa-mir-100-3p ; hsa-mir-6827-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-7111-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-5196-3p ; hsa-mir-3183 ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-6868-3p ; hsa-mir-505-5p ; hsa-mir-4290 ; hsa-mir-3194-5p ; hsa-mir-1237-3p ; hsa-mir-1248 ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-4687-5p ; hsa-mir-4667-3p ; hsa-mir-6858-3p ; hsa-mir-4494 ; hsa-mir-499b-5p ; hsa-mir-5586-5p ; hsa-mir-665 ; hsa-mir-145-3p ; hsa-mir-2355-5p ; hsa-mir-4794 ; hsa-mir-5580-5p ; hsa-mir-652-5p ; hsa-mir-664a-5p ; hsa-mir-6732-3p

Nearest miRNA

hsa-mir-12136/Upstream/1120931; hsa-mir-101-1/Downstream/1293349;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/215342, chr1-CpG: 38/Downstream/39666

Nearest cancer related gene

HIVEP3(TSG, No orient, 0)

Upstream sequence

GCACCATGAGTTGGCACTGAGGAGAATTTAGGTCTGTTCTCCCACAGAGCAAGCAATTTGCGAAACTTTGCTCTAAAACACATAAAAACCCTGGCCTTAG

Downstream sequence

CTACCAATTTTAAGGATGTTCTATTCTGCAAGGGTTCATCTTCATTCTCTCCAAAAGGATATGAGGGTCCTGCTGTATTTCAATGGAACCAGACCCCCAA