Basic Information
VIS ID
TVIS44000821
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
86352003/84592247 (Hg38)
End
86352003/84592247 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/9039694; hsa-mir-107/Downstream/1672447;
Nearest TSS
ENST00000439456/Upstream/140030; ENST00000435367/Downstream/605711;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/51050, chr10-CpG: 47/Downstream/1670636
Nearby gene
CCSER2(No orient, 73726)
Upstream sequence
GAGCCACAGGTAAATATGTGTTTGTTTATTTAAGATGAAAACGTGATTCTCTTGACTGTGAGTGCTAACCCAGAAGGCTGATTAATATCAGCTACACTCA
Downstream sequence
ATCAATCAATCATAATTTGAACACTTTACTTCTTGAAAATGGAGTTTCTTTCAAGAAAAAAATATTGAAATAGGTATTGTTTATTTAAgacttagcccta
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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