Basic Information
VIS ID
TVIS44000841
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
15806915/14434594 (Hg38)
End
15806915/14434594 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA21A
Nearest miRNA
hsa-mir-10396a/Upstream/710320; hsa-let-7c/Downstream/2104495;
Nearest TSS
ENST00000624081/Upstream/51110; ENST00000449214/Downstream/66012;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/50829, chr21-CpG: 171/Downstream/629581
Nearby gene
SAMSN1(-50634) ;
Upstream sequence
aaattatggacttcgataaatgaataacaatgcatctgtattggttcattaatcataacaaatgtaccatattacaaacaggaaaaactgagcctggagt
Downstream sequence
acatggaaactctgtgtactattttgcaaaattttctgtaaatctaaacctgttttagaaaataaagtttatttttaaaaaAAATGAAATCAGACTTCAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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