Basic Information
VIS ID
TVIS44000896
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
GRCh37/hg19
Start
33009965/31637652 (Hg38)
End
33009965/31637652 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/1262274; hsa-mir-3197/Downstream/1913010;
Nearest TSS
ENST00000624081/Upstream/77675; ENST00000476106/Downstream/21848;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/77948, chr21-CpG: 81/Downstream/21769
Nearby gene
SOD1(+21970) ;
Upstream sequence
cttgaccatttttaagtgtataattcagtagcattaagtatttcatattgttgttgaaccagtctccagacttcttttcatcctgtaaatctaaaactct
Downstream sequence
atacccattaaatgataactcttcatccctcccttgccttagcacctgtcagccaccattccactctttgtctctatggatttgactaatctgtttatct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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