Basic Information
VIS ID
TVIS44000898
Fusion event
HTLV-1-KDM2B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.31
Reference genome
End
121976552/121538647 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-let-7i/Upstream/94295; hsa-mir-3612/Downstream/1157260;
Upstream sequence
CCTGGTGGCTTAGTGACTGTGTACCCTACATCATAGCATGGTTGAGAGACTCCTTTGAGATAAATACATATTCACCgcatcatccaaactgtggtacctg
Downstream sequence
gattacttaatccaaacttcacaacaaccctaaaaagtcattcccaggattcttcctgttttcagataagcacagggaggcTTGTGACTCAAGCCTCGAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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