Basic Information
VIS ID
TVIS44000918
Fusion event
HTLV-1-LOC644215 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
99167542/97407785 (Hg38)
End
99167542/97407785 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LOC644215
Nearest miRNA
hsa-mir-107/Upstream/579021; hsa-mir-1287/Downstream/468028;
Nearest TSS
ENST00000439456/Upstream/6251; ENST00000473929/Downstream/18261;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/6426, chr10-CpG: 70/Downstream/18236
Nearby gene
RRP12(-6415) ;
Upstream sequence
GTACCCCAGGGCTCACCTCTCCACCCCTGAATTCCAGCAGTAACTCCCACCCAGAGGCTCTAGCTGTATCCATGATCAGCCCCTCCACATATGGTTAATA
Downstream sequence
AGGACCACCACATCTGTaggataggtcctgcagttagactctctgggttggaattcaagtaccaccacttgctctgtgaccttgaacaactcaccttact
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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