Basic Information
VIS ID
TVIS44000930
Fusion event
HTLV-1-LINC00587 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
105297865/102535583 (Hg38)
End
105297865/102535583 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00587
Nearest miRNA
hsa-let-7a-1/Upstream/4306366; hsa-mir-12126/Downstream/4065345;
Nearest TSS
ENST00000422679/Upstream/15947; ENST00000612124/Downstream/459728;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/796789, chr9-CpG: 38/Downstream/1463766
Upstream sequence
TACTTACTTTATAGACATGCTAAGTCATGGGAAATAATGCTTTCATTGGATTTTCTTATTTATTCTAACCTCAGTGAATTTATCATAGATACAGAAACCA
Downstream sequence
ACCTCAAAAATCGAAGGATTGCTTTATTTTTCATTCACCTGCCATTCAATTGTTAAAAAGGTGAAGTTGACTCTACCTCTTTAATATTGTTCATACCTTC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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