Basic Information
VIS ID
TVIS44000936
Fusion event
HTLV-1-CHD2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
93493105/92949875 (Hg38)
End
93493105/92949875 (Hg38)
Orient
+
Location type
Intronic
Target gene
CHD2
miRNAs that regulate target gene
hsa-mir-450a-5p ; hsa-mir-196b-5p ; hsa-mir-378a-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10393/Upstream/45400; hsa-mir-1302-10/Downstream/3383386;
Nearest TSS
ENST00000557528/Upstream/4035; ENST00000627200/Downstream/527;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/45282, chr15-CpG: 34/Downstream/94997
Upstream sequence
gtgctcaaggaattttctcagcaaggcaattttactttctgcagaaagggtgcttcttggaagcctaattgtcatgagagcacaccgaacaaagaaaagc
Downstream sequence
agaggtttttatccctgactcattgggttcttactgctgcgtcctgtctccattggctggagctggaccgcacaatctagactgattccgattggctaaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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