Basic Information
VIS ID
TVIS44000945
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
98514049/96754292 (Hg38)
End
98514049/96754292 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-107/Upstream/689893; hsa-mir-1287/Downstream/74377;
Nearest TSS
ENST00000439456/Upstream/33778; ENST00000469510/Downstream/77990;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/3622, chr10-CpG: 176/Downstream/77658
Nearby gene
PIK3AP1(-33770) ;
Upstream sequence
ACAAGCAGAAAAAGAGGGGTACATATGTGCATCCTGGGAACAAAGAAGGATATGCTCCCAAATATTAAAGTACTTGACTGACTTAGGGAAGGAGATGTTG
Downstream sequence
AGGGGCAGTATAGATGACTCTTACTTTATGCAATCCTGTGTTTAAAAATTTttacaacatggtctagcaattccactcttaggagtatagctaagggaaa
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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