Basic Information
VIS ID
TVIS44000947
Fusion event
HTLV-1-BTBD11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
107779753/107385976 (Hg38)
End
107779753/107385976 (Hg38)
Orient
-
Location type
Intronic
Target gene
BTBD11
Nearest miRNA
hsa-let-7i/Upstream/2794260; hsa-mir-1178/Downstream/1249834;
Nearest TSS
ENST00000382841/Upstream/65388; ENST00000494235/Downstream/194674;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/65646, chr12-CpG: 46/Downstream/195089
Upstream sequence
TGCCCAGCCTAGCCTGAGCCAGGACCACAGCAGGCCTGGGAAAGGGAACCCTGGAACTTTGAGGATTGTGtggagtttcacaaaacctgggtttgagtga
Downstream sequence
gaagtctggtttctggtccagctcctgttgtgtgaccttgacccagggttctctgggttagttcctcatctgtgaaaatgaggccttactagacttacct
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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