VISDB Viral Integration Site DataBase

VIS ID

TVIS44000954

Fusion event

HTLV-1-IMP4 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q21.1

Reference genome

Start

End

131104413/130346840 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-320a ; hsa-mir-4263 ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4521 ; hsa-mir-5693 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-5089-5p ; hsa-mir-4279 ; hsa-mir-1200 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-3692-5p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-6787-3p ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-4290 ; hsa-mir-8064 ; hsa-mir-7113-3p ; hsa-mir-7160-3p ; hsa-mir-6752-3p ; hsa-mir-1273g-3p ; hsa-mir-1288-5p ; hsa-mir-221-5p ; hsa-mir-377-5p ; hsa-mir-4327 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4683 ; hsa-mir-4768-3p ; hsa-mir-4786-5p ; hsa-mir-4793-3p ; hsa-mir-4793-5p ; hsa-mir-4794 ; hsa-mir-498 ; hsa-mir-500a-3p ; hsa-mir-508-5p ; hsa-mir-541-3p ; hsa-mir-5694 ; hsa-mir-6086 ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6502-3p ; hsa-mir-6504-3p ; hsa-mir-6512-3p ; hsa-mir-6516-5p ; hsa-mir-654-5p ; hsa-mir-664a-5p ; hsa-mir-6720-5p ; hsa-mir-6721-5p ; hsa-mir-6849-3p ; hsa-mir-6888-5p ; hsa-mir-766-3p ; hsa-mir-767-5p ; hsa-mir-7703 ; hsa-mir-8073

Nearest miRNA

hsa-mir-1285-2/Upstream/2923222; hsa-mir-10b/Downstream/1144320;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/3550, chr2-CpG: 123/Downstream/8677

Nearby gene

IMP4(+216) ;

Upstream sequence

ACAGAGAGAGAGATTTGATGCTAACGTCCCCTCAAGAGTGAGGGTCATATGAGCTCTTCAGCAGGCAGATGTGGGTAGCAGGGCCAGCCTGTGTCAGGGG

Downstream sequence

CAGCCCACCAAGTTAACTCACTGAGTGGAAGCCGCCAGTGTGCCAACGCGGAGGGGACAGGCCACACCCAGTGCTCAGCAGCTgattcctcatgtaagtg