Basic Information
VIS ID
TVIS44000965
Fusion event
HTLV-1-PPP1R16A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145710128/144484745 (Hg38)
End
145710128/144484745 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
PPP1R16A
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-10400/Upstream/22206; hsa-mir-6850/Downstream/307186;
Nearest TSS
ENST00000518652/Upstream/6394; ENST00000533829/Downstream/5285;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/6226, chr8-CpG: 111/Downstream/15332
Nearby gene
FOXH1(-8410) ;
Upstream sequence
GAAGAGGGAGATGCAACGCTTCCCCTGGTTTCTGGGGAGAGGCTTCCCCAATTCTCCAGCCCCTGACAGACATTGCGTGAGAGCTCATGGTTAGCGGGCC
Downstream sequence
AGTCCCTGGTGTGGTCCACGCGTATCTCCTGTCCCGGGCTGGAAGCATGATGTGTGCAAATGTCCAAATCACGGGGTCTTCCCTCCCTCACAGGGCTTTA
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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