Basic Information
VIS ID
TVIS44000994
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
53652933/55985702 (Hg38)
End
53652933/55985702 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/506404; hsa-mir-122/Downstream/2465372;
Nearest TSS
ENST00000575820/Upstream/65503; ENST00000588803/Downstream/12637;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/205091, chr18-CpG: 57/Downstream/652486
Nearby gene
LINC01416(No orient, 65503)
Upstream sequence
ttacctccaccttagctcaatgttacagaagctttgccctaggcataaacagccaagtagacaggggttccttctccctccatctccaagtctgggctat
Downstream sequence
ggtttgattcaggaaaggacaggctgttggcatttctctccctccagcctcacatgtagaagcttgattccaagtaggtgcacccaagaCAGCTAGCTtt
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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