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TVIS44000995
Basic Information
VIS ID
TVIS44000995
Fusion event
HTLV-1-NIPA1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
23045073/22827993 (Hg38)
End
23045073/22827993 (Hg38)
Orient
-
Location type
UTR3
Target gene
NIPA1
miRNAs that regulate target gene
hsa-mir-9-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-96-5p
;
hsa-mir-877-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-4652-3p
;
hsa-mir-4743-3p
;
hsa-mir-548aw
;
hsa-mir-3686
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-3607-3p
;
hsa-mir-8084
;
hsa-mir-519b-3p
;
hsa-mir-519c-3p
;
hsa-mir-519a-3p
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-4796-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-17-5p
;
hsa-mir-106a-5p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-454-3p
;
hsa-mir-3666
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-301b-3p
;
hsa-mir-4295
;
hsa-mir-301a-3p
;
hsa-mir-6749-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-6847-3p
;
hsa-mir-149-5p
;
hsa-mir-7113-3p
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-6791-5p
;
hsa-mir-4292
;
hsa-mir-4308
;
hsa-mir-5196-3p
;
hsa-mir-4314
;
hsa-mir-6826-3p
;
hsa-mir-3182
;
hsa-mir-6776-5p
;
hsa-mir-6861-5p
;
hsa-mir-6845-3p
;
hsa-mir-6795-3p
;
hsa-mir-6887-3p
Nearest miRNA
hsa-mir-1268a/Upstream/602664; hsa-mir-10393/Downstream/369834;
Nearest TSS
ENST00000557528/Upstream/41180;
ENST00000560762/Downstream/10648;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/40367
,
chr15-CpG: 65/Downstream/10571
Upstream sequence
AGAACACGGAAGCTAATCCATGCTGTCGGGAACAGACCTTACACTGAAATGTTCTCTTTCTAGTTTCCTGCTTGGTGGCAGGAAGCCTAAGTCAGCATCG
Downstream sequence
AGCAGGTGTCAGGTCGAAGCGGCACAACGGGAGGGGCTCTGGGAACCACCGGAGTACTCTCTCCCCTCTTCTGGGTTAGCTGAGCAGCTTGAAGAAGAGG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Sample Information
×
Sample name
ATL11-CR1
Sample type
Nontumor
Age
27
Gender
Male
CpG Island Information
×
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