Basic Information
VIS ID
TVIS44000997
Fusion event
HTLV-1-AOAH integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
36588085/36548479 (Hg38)
End
36588085/36548479 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7C
Target gene
AOAH
Nearest miRNA
hsa-mir-1183/Upstream/1607645; hsa-mir-10399/Downstream/370878;
Nearest TSS
ENST00000635602/Upstream/17795; ENST00000419326/Downstream/1777;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/158282, chr7-CpG: 136/Downstream/899272
Upstream sequence
ttcaccatgttggccaggctggtctccaactcctgacctcaggtgatctgcccacctcggcctcccaaagtgctgggattataggtgtgagcccctgtgc
Downstream sequence
ccggccGTGCTTCTAAGATAGAGAAATTCAGCTGAACAGCAGGCTGCTATAATGGAGTGGAGTTGGTGAGGAGAGGGTGGGGAAGAGCCCAGAGCCAAAG
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
Curate