Basic Information
VIS ID
TVIS44001004
Fusion event
HTLV-1-LINC01818 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
151081838/150225324 (Hg38)
End
151081838/150225324 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LINC01818
Nearest miRNA
hsa-mir-128-1/Upstream/894951; hsa-mir-10b/Downstream/1143010;
Nearest TSS
ENST00000437798/Upstream/53901; ENST00000416350/Downstream/31683;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/894346, chr2-CpG: 118/Downstream/259904
Nearby gene
RND3(-242869) ;
Upstream sequence
aatgcaaacataagcatttaattatgatacaaCCAACATGTATGTCCTAACACAGCATTTCTCAAAATGGATTCCATAGACTTTCCAGTCTTTTCCCTAA
Downstream sequence
GGTGTGTGAATCAATCTgggccagagagatccaactgtacttaaatctcagttccactgttactggtggaagagatctgagttaccctgagttaccccag
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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