Basic Information
VIS ID
TVIS44001038
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
34352546/33883340 (Hg38)
End
34352546/33883340 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/2868598; hsa-mir-1185-1/Downstream/3068969;
Nearest TSS
ENST00000550708/Upstream/148099; ENST00000555922/Downstream/47996;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/82108, chr14-CpG: 98/Downstream/66962
Nearby gene
EGLN3(-40875) ;
Nearest cancer related gene
EGLN3(TSG, -40875) ;
Upstream sequence
ATTATtttttagaaaatacacactgaggtgtttaaaaataaaggggaatcatatctgcaacttagtcttaaacagttcagaaaaaaaaaaggtgtgtgat
Downstream sequence
acatatacatttatctatcgagaaaaggttacagtaagtgtaataaaatgttaacatttggggtatctgggtagaagttatctaggaattttttgaacta
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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