Basic Information
VIS ID
TVIS44001049
Fusion event
HTLV-1-LOC107986324 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
160540741/159619589 (Hg38)
End
160540741/159619589 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107986324
Nearest miRNA
hsa-mir-12113/Upstream/490695; hsa-mir-1305/Downstream/3473985;
Nearest TSS
ENST00000502981/Upstream/221056; ENST00000512652/Downstream/158195;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/515606, chr4-CpG: 71/Downstream/3546720
Nearby gene
RAPGEF2(+259440) ;
Upstream sequence
CAGTCCCCATTGGCAATGATTAATGTTAATTTTTCCATCTCAAATCTTTTATGAATAACTTGAATGGGTGAAGGAGCAGATTAAACcatatattgaacaa
Downstream sequence
atattgattgagtgcttcctatctatcaggcatcatgcttggtgctggaaatgtagcatgaaaaaggtcaccagtgaatctgccctcaatgagtttggga
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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