Basic Information
VIS ID
TVIS44001060
Fusion event
HTLV-1-APBB1IP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
26777682/26488753 (Hg38)
End
26777682/26488753 (Hg38)
Orient
+
Location type
Intronic
Target gene
APBB1IP
Nearest miRNA
hsa-mir-1265/Upstream/2212972; hsa-mir-107/Downstream/1800505;
Nearest TSS
ENST00000439456/Upstream/50328; ENST00000493857/Downstream/73190;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/49690, chr10-CpG: 55/Downstream/78224
Upstream sequence
CACCTGCAGCCATCTTCCTCTCTTCTAGGTGCCATAAACACTTTTTTAATCCCAACAATACACACAAAATAGGACAAGGATCTTCCATCATCCGTCACTG
Downstream sequence
ATGCTGTGTTTGATTCCTCTCTGACTTTCCCTGCACACATAGACCTAGACCTTCGGTGTTTTTCTCACCTGTTGCTTCTATACCTGGGTGCTCACCTGCC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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