Basic Information
VIS ID
TVIS44001071
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
41820838/43743470 (Hg38)
End
41820838/43743470 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1180/Upstream/298585; hsa-mir-10226/Downstream/464301;
Nearest TSS
ENST00000595228/Upstream/63197; ENST00000590148/Downstream/15318;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/22457, chr17-CpG: 75/Downstream/11796
Nearby gene
SOST(-10261) ;
Upstream sequence
tggccgggcatagtggctcatgcctataatcccagcactttgggaggccaaggtgggcagatcacttgaggtcgggagttcgagaccagcctggacaaca
Downstream sequence
tggtgaaaccccatctctactaacaatacaaaaattagccaggcgtggtggcatgtgcctgtagtcccagctactcaggaggctgaggcaggagaatcgc
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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