Basic Information
VIS ID
TVIS44001082
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2017
PubMed ID
28811663
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q12
Reference genome
GRCh37/hg19
Start
39921987/60951496 (Hg38)
End
39921987/60951496 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA9F
Nearest miRNA
hsa-mir-101-2/Upstream/19717661; hsa-let-7a-1/Downstream/9858479;
Nearest TSS
ENST00000422679/Upstream/37122; ENST00000622899/Downstream/4990;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/103819, chr9-CpG: 36/Downstream/145277
Nearby gene
FAM74A1(+15768) ;
Upstream sequence
TGGTTAACTTTTAAATAACTAGTTAATCTTTATTATGAAATAAGAATTTTGGAAGAGGCGAAGTGATCTATATACATGGGATGGAGGAAAGTGAATATCA
Downstream sequence
ATGGCCTATGACGCATCATTAAGTTTCTTTTCTATTTCATAGAATTTTCTACTCACATTACTGTCTTATTCAGTGTTCTTTTGTTTGGTGTTGAACCAGC
Reference
Artesi, M., et al.Monitoring molecular response in adult T-cell leukemia by high-throughput sequencing analysis of HTLV-1 clonality. Leukemia ,2017,31(11): 2532-2535.
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